About NIMH

National Institute of Mental Health originated from Prague Psychiatric Centre on 1st January 2015 and is located at Topolová 748, 250 67 Klecany. The establishment of a new modern centre oriented on research and clinical care was made possible by a project financed by Operational Programme Research and Development for Innovation. NIMH is meant to become national reference institution for the field of mental health.
NIMH programme is focused on researching neurobiological mechanisms that lead to development of severe mental disorders (schizophrenia, depression, anxiety and stress reactions). Research also includes development and testing of new diagnostic and therapeutic methods. Our approach is based upon interconnection of methods of molecular biology, animal modelling and clinical research and testing.

Neurobiology of Mental Illness: Research of neurobiological mechanisms that lead to development of severe mental disorders (schizophrenia, depression, anxiety states and stress reactions). The research also includes development and testing of new diagnostic and therapeutic methods. Our approach is based upon interconnection of methods of molecular biology, animal modelling and clinical research and testing.

Neurobiology of Ageing and Dementia: Research of changes in brain in the process of getting old and development of methods to detect early cognitive disorders, dementias and in particular Alzheimer’s disease. The output from brain imaging, neuropsychological and biochemical methods is used to develop techniques of early diagnosing and identifying possible Alzheimer’s patients.

Biological Nature of Addictions: Research of neuronal mechanisms of dependence formation and of new therapeutic possibilities, as well as biological and pharmacological characteristics of existing and especially new synthetic drugs emerging at world market. Output is applied in primary prevention and risk reduction. The main objective is to develop substances and other therapeutic means capable of treating dependencies and prevent them from progressing.

Epidemiology of Mental Illness: The objective of this research is to provide outcome of nationwide epidemiological survey of mental disorders incidence among Czech population with seven-year periodicity. The results will bring basic data for rational planning of a psychiatric service network, orientation of preventive and educational programmes aimed at addictions and other mental health disorders. The programme will issue proposals for specific measures to be taken in order to improve mental health care system.

System of Psychiatric Care in the Czech Republic Based upon Facts: Research in the field of social psychiatry will use analyses and both nationwide and international comparative studies to bring facts about expensiveness and effectivity of psychiatric care systems. Comparisons of various types of intervention, services and complex care systems (psychiatric care models), analysis and prediction of expenses and demands, will provide hard data needed for knowledgeable adjustment of psychiatric care system in the Czech Republic.

New Technologies in Mental Health Improvement: The objective is to create an electronic system capable of integrating all patient’s data from mobile applications with present therapeutic information, brain imaging output, presence of risky gene variants and other biomarkers. Resulting individualized complex database will then, thanks to specific mathematical analytical tools, provide expert recommendations towards therapy optimisation. An electronic hospital system will also connect NIMH with doctors’ offices and providers of rehabilitation and social services.

Treatment and Research of Sleep Disorders and Biological Rhythms Disturbances: The sleep medicine programme is focused on researching, diagnosing and treating sleep and circadian rhythm disorders. Sleep regulation, changes in sleep/awake rhythms and impacts of overuse or dependence on hypnotics are studied on several levels. The main aim is to improve objective diagnostics of sleep disorders and therapeutic predictions through new mathematical methods in computer analysis of biosignal including polysomnograms. Findings are immediately used in clinical practice as guidelines and recommendations for improvement of early diagnostics and therapy optimization.

The main objective of NIMH Clinical Centre as the national reference institution is to form a base for development, testing and introducing latest therapeutic methods into practice, for creating medical standards, and for training experts. Special attention is paid to research and treatment of mood disorders, anxiety disorders, psychotic disorders and mental disorders in old age including dementias. NIMH has inpatient wards (60 beds in total), a day care centre, memory disorders counselling office and specialized outpatient departments. NIMH Clinical Centre accepts patients from all regions of the Czech Republic on the basis of their clinical profile and current research programmes.

NIMH is also a training base for medical students of the Third Faculty of Medicine at Charles University in Prague and for other master’s and postgradual programmes (psychology, neurosciences, biology, sociology, epidemiology etc.).

 

 

 


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