RNDr. Tomáš Petrásek, Ph.D.
researcher
working at:  RP1 Experimental Neurobiology
in the institution:  2014 - present
telephone: (+420) 283 088 246
e-mail: Tomas.Petrasek@nudz.cz
curriculum vitae


ResearchGate

Selected publications:

 Petrasek, T., Vojtechova, I., Lobellova, V., Popelikova, A., Janikova, M., Brožka, H., ... & Valeš, K. (2018). McGill transgenic rat model of Alzheimer's disease displays cognitive and non-cognitive impairments and altered circadian clock function. Frontiers in aging neuroscience, 10, 250. Dr. Jan Bureš Award for the best Alzheimer's research paper in 2018, awarded by Alzheimer Foundation

 Vojtechova, I., Petrasek, T., Maleninska, K., Brozka, H., Tejkalova, H., Horacek, J., ... & Vales, K. (2018). Neonatal immune activation by lipopolysaccharide causes inadequate emotional responses to novel situations but no changes in anxiety or cognitive behavior in Wistar rats. Behavioural brain research, 349, 42-53.

 Petrasek T, Doulames V, Prokopova I, Vales K, Stuchlik A. (2010): Combined administration of alpha1-adrenoceptor antagonist prazosin and beta-blocker propranolol impairs spatial avoidance learning on a dry arena. Behav Brain Res., 2010, 208(2):402-7.

 Krištofiková, Z., Vrajová, M., Šírová, J., Valeš, K., Petrásek, T., Schönig, K., ... Řípová, D. (2013). N-methyl-D-aspartate receptor–nitric oxide synthase pathway in the cortex of Nogo-A-deficient rats in relation to brain laterality and schizophrenia. Frontiers in behavioral neuroscience, 7.

 Petrasek, T., Prokopova, I., Bahnik, S., Schonig, K., Berger, S., Vales, K., Tews, B., Schwab, M.E., Bartsch, D., Stuchlik, A. (2014): Nogo-A downregulation impairs place avoidance in the Carousel maze but not spatial memory in the Morris water maze. Neurobiology of Learning and Memory, 107:42-9.

 Petrasek, T., Prokopova, I., Sladek, M., Weissova, K., Vojtechova, I., Bahnik, S., Zemanova, A., Schonig, K., Berger, S., Tews, B., Bartsch, D.,  Schwab, M.E., Sumova, A., Stuchlik, A. (2014): Nogo-A-deficient transgenic rats show deficits in higher cognitive functions, decreased anxiety and altered circadian activity patterns. Frontiers in Behavioral Neuroscience, 8.

 Petrasek, T., Skurlova, M., Maleninska, K., Vojtechova, I., Kristofikova, Z., Matuskova, H., Sirova, J., Vales, K., Ripova, D., Stuchlik, A. (2016): A rat model of Alzheimer´s disease based on Abeta42 and pro-oxidative substances exhibits cognitive deficit and alterations in glutamatergic and cholinergic neurotransmitter systems. Frontiers in Aging Neuroscience, 8.

 Vojtechova, I, Petrasek, T, Hatalova, H, Pistikova, A, Vales, K, Stuchlik, A. (2016): Dizocilpine (MK-801) impairs learning in the active place avoidance task but has no effect on the performance during task/context alternation. Behavioural Brain Research, 305:247-257.

 Petrasek, T., Skurlova, M., Maleninska, K., Vojtechova, I., Kristofikova, Z., Matuskova, H., ... & Stuchlik, A. (2016). A Rat Model of Alzheimer’s Disease Based on Abeta42 and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems. Frontiers in aging neuroscience, 8.

Professional training and experience

2007 - present: Institute of Physiology of the Czech Academy of Sciences, Department of Neurophysiology of Memory
2014 - present: Prague Psychiatric Center/NIMH

Bachelor thesis

2004 - 2007: Spatial navigation of laboratory rats in experimental mazes

Master thesis

2007 - 2009: The effect of antagonism of adrenergic receptors on spatial learning in laboratory rats

Awards and honors

2018 - 2018: Jan Bureš Award for a best research paper on Alzheimer's disease awarded by Alzheimer Foundation

Thesis

2009 - 2014: Learning and memory in Nogo-A knockdown rats

Publications

Most important publications

PETRÁSEK, T., SKURLOVA, M., MALENINSKA, K., VOJTĚCHOVÁ, I., KRIŠTOFIKOVÁ, Z., MATUŠKOVÁ, H., ŠÍROVÁ, J., VALEŠ, K., ŘÍPOVÁ, D., STUCHLÍK, A. A rat model of Alzheimer’s disease based on Abeta42 and Pro-oxidative substances exhibits cognitive deficit and alterations in glutamatergic and cholinergic neurotransmitter systems. Frontiers in Aging Neuroscience. 2016, 8(April), "Article number 83". ISSN 1663-4365. DOI: 10.3389/fnagi.2016.00083. IF 4.348.


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RP1 Experimental Neurobiology RP2 Public Mental Health RP3 Applied Neuroscience and Neuroimaging RP4 Epidemiological and Clinical Research in Addictions RP5 Sleep Medicine and Chronobiology RP6 Brain Electrophysiology RP7 Clinical Research of Mental Disorders RP8 Translational Neuroscience International Cooperation Department AD Centrum Publications Ongoing Projects Pharmaceutical Industry-Sponsored Research Ethics Commission Postgraduate Students Conferences & Seminars Awards International Course 2015
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