Ongoing Projects

NATIONAL PROJECTS (EXCEPT OPERATIONAL PROGRAMMES)

The Czech Science Foundation

Characterizing State Repertoire and Dynamics of Spontaneous Brain Activity by Neuroimaging
(21-32608S)
Investigator: MUDr. Martin Brunovský, Ph.D.
Principle investigator: NIMH
Co-investigator/Partner: Institute for Computer Science CAS
Duration: 1.4.2021–1.3.2024
Total budget: 11 368 000 CZK
Total budget NIMH: 6 833 000 CZK

Nationwide Research of Sexual Behaviour, Preferences, and Wellbeing in The Czech Population: Current Situation and Trends (21-31490S)
Investigator: prof. PhDr. Petr Weiss, Ph.D., DSc.
Principle investigator: NIMH
Duration: 1.7.2021–1.6.2024
Total budget NIMH: 6 550 000 CZK

Learning Synchronization Patterns in Multivariate Neural Signals for Prediction of Response to Antidepressants (21-14727K)
Investigator: MUDr. Martin Brunovský, Ph.D.
Principle investigator: Institute for Computer Science CAS
Co-investigator/Partner: NIMH
Duration: 1.4.2021–31.03.2024
Total budget: 9 620 000 CZK
Total budget NIMH: 2 086 000 CZK

Prevalence of High risk Symptoms for Psychosis and Their Relationship to Neurocognitive Performance and Daily Functioning in Population of Adolescents (18-03125S)
Investigator: PhDr. Mabel Virginia Rodriguez Manchola, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2018–30.6.2021
Total budget NIMH: 5 208 000 CZK

Cognitive Superaging (18-06199S)
Investigator: MUDr. Miloslav Kopeček, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2018–30.6.2021
Total budget NIMH: 4 503 000 CZK

Socio-economic Determinants of Premature Mortality Related to Alcohol and Tobacco Use – Spatially Integrated Approach (18-17564S)
Investigator: Mgr. Ladislav Kážmér, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2018–30.6.2021
Total Budget NIMH: 2 871 000 CZK

Electromagnetic Models of Animal Brains (18-16218S)
Investigator: MUDr. Tomáš Páleníček, Ph.D.
Principal investigator: Brno University of Technology (prof. Dr. Ing. Zbyněk Raida)
Co-investigator-Partner: NIMH
Duration: 1.1.2018–30.6.2021
Total bugnet: 7 240 000 CZK
Total budget NIMH: 3 811 000 CZK

Inter-individual Differences in Subjective Time (19-15728S)
Investigator: prof. MUDr. Jiří Horáček, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 6 955 000 CZK

Aversive Response to Spiders and the Underlying Emotions (19-07164S)
Investigator: RNDr. Eva Landová, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 8 690 000 CZK

The Stranger as a Symbol of Otherness – How Personality Influences Our Attitudes (19-10057S)
Investigator: doc. PhDr. Marek Preiss, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 4 282 000 CZK

Psychology of Male Intra-sexual Competition and Associated Neural Correlates (19-11822S )
Investigator: Mgr. Vít Třebický, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 6 482 000 CZK

Minority Stress in Non-heterosexuals in the Czech Republic (19-14801S)
Investigator: RNDr. Michal Pitoňák, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 3 414 000 CZK

Influence of Girls’ Expressiveness and Nonverbal Communication Towards Peers on Their Social Functioning During Ontogenesis (19-17540S)
Investigator: Mgr. et Mgr. Jitka Lindová, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 4 640 000 CZK

Specific Serotonin-dopamin Modulators and Their Potential in the Model of Induced Psychosis
(19-11332S)
Investigator: PharmDr. Jan Korábečný, Ph.D.
Principle investigator: University Hospital Hradec Králové (PharmDr. Ondřej Soukup, Ph.D.)
Co-investigator-Partner: NIMH
Duration: 1.1.2019–31.12.2021
Total budget: 8 872 000 CZK
Total budget NIMH: 4 973 000 CZK

The Role of Inferior Parietal Lobe in Self-Agency (20-24782S)
Investigator: prof. MUDr. Pavel Mohr, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2020–31.12.2022
Total budget NIMH: 7 731 000 CZK

Psychoplastogenicity of Psilocybin – the Interplay of Serotonergic Mechanisms, Sleep-wake Cycle and Neuroplasticity on Memory Consolidation (20-25349S)
Investigator: doc. RNDr. Zdeňka Bendová, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2020–31.12.2022
Total budget NIMH: 12 029 000 CZK

Impact of Media News on Mental Health: Cognitive and Neural Mechanisms  (20-13458S)
Investigator: doc. PhDr. Ladislav Kesner, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2020–31.12.2022
Total budget NIMH: 6 740 000 CZK

Novel Neuroprotective Compounds Based on NMDA Receptor Antagonism and Cholinergic Stimulation (20-12047S)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: University Hospital hradec Králové (PharmDr. Ondřej Soukup, Ph.D.)
Co-investigators/Partners: NIMH; Institute of Experimental Medicine CAS (Mgr. Martin Horák Ph.D.)
Duration: 1.1.2020–31.12.2022
Total budget: 14 980 000 CZK
Total budget NIMH: 4 996 000 CZK

Relationship between Neurocognitive Profile and Cognitive Reserve in Patients with a First Episode Schizophrenia Disorder (21-03615S)
Investigator: PhDr. Mabel Virginia Rodriguez Manchola, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2021–31.12.2023
Total budget NIMH: 7 054 000 CZK
 

The Czech Research Council

Psilocybin Versus Ketamine – Fast Acting Antidepressant Strategies in Treatment-Resistant Depression (NU21-04-00307)
Investigator: MUDr. Tomáš Páleníček, Ph.D.
Principle investigator: NIMH
Co-investigator/Partner: University of Chemistry and Technology, Faculty of Food and Biochemical Technology
Duration: 1.5.2021–31.12.2024
Total budget: 12 699 000 CZK
Total budget NIMH: 10 223 000 CZK

Novel Model of Schizophrenia Based on Gnathonemus Petersii Species Enriched by the Electrical Communication and Social Behaviour Evaluation (NU21-04-00405)
Investigator: prof. MUDr. Jiří Horáček, Ph.D., FCMA
Principle investigator: NIMH
Co-investigator/Partner: Charles University, Faculty of Science
Duration: 1.5.2021–31.12.2024
Total budget: 9 713 000 CZK
Total budget NIMH: 6 156 000 CZK

Predicting Functional Outcome in Schizophrenia from Multimodal Neuroimaging and Clinical Data (NU21-08-00432)
Investigator: MUDr. Filip Španiel, Ph.D.
Principle investigator: Institute for Computer Science CAS
Co-investigator/Partner: NIMH
Duration: 1.5.2021–31.12.2024
Total budget: 13 897 000 CZK
Total budget NIMH: 8 481 000 CZK

Concurrence of the Rheumatic and Psychiatric Diseases: Epidemiology, Identification of the Risk-Group Population and Economic Costs (NU21-09-00297)
Investigator: PhDr. Petr Winkler, Ph.D.
Principle investigator: Institute of Rheumatology
Co-investigator/Partner: NIMH
Duration: 1.5.2021–31.12.2024
Total budget: 12 790 000 CZK
Total budget NIMH: 6 331 000 CZK

Deficits in the Sociosexual Functioning of Patients with First Episodes and Early Onset Schizophrenia: Impact on Disease Progression and Sexological Remediation Strategies (NU21J-04-00024)
Investigator: Mgr. Renáta Androvičová, Ph.D.
Principle investigator: NIMH
Duration: 1.5.2021–31.12.2024
Total budget NIMH: 6 901 000 CZK

Effectiveness of Remote Peer Support in Prevention of Postpartum Depression: A Randomized Controlled Trial (NU21J-09-00064)
Investigator: MUDr. Antonín Šebela, Ph.D.
Principle investigator: NIMH
Duration: 1.5.2021–31.12.2024
Total budget NIMH: 5 845 000 CZK

The Interplay Between the Gut Microbiota and Brain Functions: Implication for Metabolome and
Metabolic Syndrome in Schizophrenia (17-31852A)
Investigator: MUDr. Tomáš Páleníček, Ph.D.
Principle investigator: NIMH
Co-investigator-Partner: Institute of Animal Physiology and Genetics of the CAS
(RNDr. Kateřina Fliegerová, CSc.)
Duration: 1.4.2017–31.12.2021
Total budget: 13 553 000 CZK
Total budget NIMH: 10 163 000 CZK

Developmental Dynamics of Clinical and Neurophysiological Features in Children and Adolescents at Genetic Risk of Bipolar Affective Disorder (17-32478A)
Investigator: MUDr. Tomáš Novák, Ph.D.
Principle investigator: Motol University Hospital (MUDr. Michal Goetz, Ph.D.)
Co-investigator-Partner: NIMH
Duration: 1.4.2017–31.12.2021
Total budget: 8 157 000 CZK
Total budget NIMH: 3 501 000 CZK

Clinical and Neurobiological Predictors of Response to Ketamine: Towards Personalized Treatment of Depression (NV18-04-00260)
Investigator: prof. MUDr. Jiří Horáček, Ph.D. FCMA
Principle investigator: NIMH
Duration: 1.5.2018–31.12.2021
Total budget NIMH: 10 078 000 CZK

Sleep and Brain Changes Related to Memory Decline in Mild Cognitive Impairment
(NV18-07-00272)
Investigator: doc. MUDr. Aleš Bartoš, Ph.D.
Principle investigator: NIMH
Duration: 1.5.2018–31.12.2021
Total budget NIMH: 9 443 000 CZK

Overlap of Neurodegenerative Dementias and Their Clinic-pathological Correlations: A Prospectiveretrospective Multicentric Study (NV19-04-00090)
Investigator: doc. MUDr. Aleš Bartoš, Ph.D.
Principal investigator: Thomayer Hospital (doc. MUDr. Radoslav Matěj, Ph.D.)
Co-investigator-Partners: NIMH; University Hospital Olomouc (doc. MUDr. Kateřina Menšíková, Ph.D.); Hospital Na Homolce (MUDr. Jiří Keller, Ph.D.); General University Hospital in Prague (prof. MUDr. Jan Roth, CSc.)
Duration: 1.5.2019–31.12.2022
Total budget: 15 127 000 CZK
Total budget NIMH: 1 580 000 CZK
 

Obsessive-compulsive Disorder as a Decision-making Disease: Translational Probe of Aberrant Error Signalling and Coordination of Brain Networks Targeting Causal Interactions and Clues for Therapy (NU20-04-00147)
Investigator: prof. MUDr. Jiří Horáček, Ph.D., FCMA
Principle investigator: NIMH
Project partner: Fyziologický ústav AV ČR
Duration: 1.5.2020–31.12.2023
Total budget: 13 941 000 CZK
Total budget NIMH: 8 092 000 CZK

Role of Neuroactive Steroids in Mechnanism of Action of Clozapine (NU20-04-00389)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: NIMH
Project partners: Institute of Endocrinology Prague, Institute of Physiology CAS
Duration: 1.5.2020–31.12.2023
Total budget: 18 949 000 CZK
Total budget NIMH: 8 358 000 CZK

Obesity as a Risk Factor for Adverse Brain, Cognitive and Clinical Outcomes in Schizophrenia – Prospective Study (NU20-04-00393)
Investigator: MUDr. Filip Španiel, Ph.D.
Principle investigator: NIMH
Duration: 1.5.2020–31.12.2023
Total budget: 11 774 000 CZK

Healthy Brain Aging: A life-course perspective (NU20J-04-00022)
Investigator: MUDr. Antonín Šebela, Ph.D.
Principle investigator: NIMH
Project partner: Masaryk University
Duration: 1.5.2020–31.12.2023
Total budget: 11 277 000 CZK
Total budget NIMH: 3 885 000 CZK

Dually Acting Cognitive Enhancers for Palliative Treatment of Alzheimer´s Disease
(NU20-08-00296)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: University Hospital Hradec Králové
Project partners: NIMH, Institute of Experimental Medicine Prague
Duration: 1.5.2020–31.12.2023
Total budget: 16 691 000 CZK
Total budget NIMH: 5 701 000 CZK

Gut Microbiome and Autoimmune Mechanisms in Patients with Central Hypersomnia
(NU20-04-00088)
Investigator: MUDr. Jitka Bušková, Ph.D.
Principle investigator: General University Hospital in Prague
Project partners: NIMH, Institute of Microbiology CAS
Duration: 1.5.2020–31.12.2023
Total budget: 13 999 000 CZK
Total budget NIMH: 1 807 000 CZK

Central Bohemia region

Multi-purpose Synchronization Device for EEG Research (S-1270/REG/2021)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: ESSENCE LINE, s.r.o.
Duration: 1.4.2021–30.6.2021
Total budget NIMH: 209 029 CZK

The Technology Agency of The Czech Republic

Virtual City – Serious Game Battery for Cognitive Training and Daily Activities Practice in Ecologically Valid Virtual Environement (TL01000309)
Investigator: Mgr. et Mgr. Iveta Fajnerová, Ph.D.
Principle investigator: NIMH
Co-investigator-Partner: 3dsense, s. r. o.
Duration: 1.3.2018–31.12.2021
Total budget: 9 704 706 CZK
Total budget NIMH: 4 261 706 CZK

Development of Tools for Predicting School Success at Pre-School Age: The Cumulative Risk Index and Screening of Affective and Cognitive Functions Using Interactive Computer Games (TL02000561)
Investigator: RNDr. PhDr. Tereza Nekovářová, Ph.D.
Principle investigator: NIMH
Co-investigator-Partner: 3dsense, s. r. o.
Duration: 1.1.2019–31.12.2021
Total budget: 6 389 295 CZK
Total budget NIMH: 2 624 895 CZK

Application of Research Methods to Design a System of Services for Psychedelic Users (TJ02000156)
Investigator: Mgr. Rita Kočárová
Principle investigator: NIMH
Duration: 27.3.2019–28.2.2021
Total budget NIMH: 2 178 482 CZK

BrainTech: Innovative Technologies for Psychiatry and Clinical Neuroscience (BrainTech) (TP01010062)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2020–31.12.2022
Total budget NIMH: 14 970 000 CZK

Subjects
Compact System for Measuring Autonomous Regulation of the Sensory System (COMSYMARSES)
Investigator: Mgr. Přemysl Vlček, Ph.D.
Duration: 1.9.2020–31.8.2022
Budget: 1 696 000 CZK

Multipurpose Event Synchronization Device for EEG Research and Brain Computer Interface Application
Investigator: Ing. Vlastimil Koudelka, Ph.D.
Duration: 1.8.2020–31.12.2021
Budget: 1 100 000 CZK

BASS Assay: Development, Evaluation, and Validation of a Blood Circulating Biomarker Assay to Subtype Schizophrenia
Investigator: MUDr. Filip Španiel, Ph.D.
Duration: 1.8.2020–30.4.2021
Budget: 2 200 000 CZK

VR House – Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder
Investigator: Mgr. et Mgr. Iveta Fajnerová, Ph.D.
Duration: 1.8.2020–30.10.2022
Budget: 1 431 000 CZK

Validation of the Method for the CBD and THC Quantification in CBD-rich Supplements
Investigator: Ing. Martin Kuchař, Ph.D.
Duration: 1.9.2020–30.4.2022
Budget: 1 900 000 CZK

Portable Eye-brain Pupillometric Diagnostic Device (PEBDI)
Investigator: Ing. Eduard Bakštein, Ph.D.
Duration: 1.9.2020–31.8.2022
Budget: 1 352 000 CZK

Exposure to Stresful Situations in a Virtual City Enviroment (TL03000223)
Investigator: Mgr. et Mgr. Iveta Fajnerová, Ph.D.
Principle investigator: NIMH
Co-investigator-Partner: Czech Technical University in Prague
Duration: 1.4.2020–31.12.2023
Total budget: 14 069 388 CZK
Total budget NIMH: 5 627 188 CZK

Alivio Mobile Game Reducing OCD Symptoms (TL03000637)
Investigator: MUDr. Pavla Stopková, Ph.D.
Principle investigator: Pixelfield s.r.o.
Co-investigator-Partner: NIMH
Duration: 1.4.2020–31.3.2022
Total budget: 6 481 426 CZK
Total budget NIMH: 1 827 301 CZK

Training Aimed at Increasing Police Prepardness for Mentally and Communication-Intensive Situations Using Virtual Reality (TL03000050)
Investigator: Mgr. Eliška Procházková, Ph.D.
Principle investigator: NIMH
Co-investigator-Partner: Leiden University, 3dsense, s.r.o.
Duration: 1.8.2020–31.8.2023
Total budget: 13 639 695 CZK
Total budget NIMH: 2 585 919 CZK

Effectiveness of the System of Addictology Services in the Czech Republic in Connection with the COVID-19 Pandemic (TL04000382)
Investigator: Mgr. Barbora Orlíková, Ph.D.
Investigator: NIMH
Principle investigator: CETA – Centre for Economic and Market Analyses; Jan Evangelista Purkyně University in Ústí nad Labem
Duration: 1.10.2020–30.9.2022
Total budget: 3 706 069 CZK
Total budget NIMH: 1 371 207 CZK

You are Not Alone: Software to Reduce Psychosocial Stress (TL04000197
Investigator: MUDr. Antonín Šebela, Ph.D.
Principle investigator: NIMH
Duration: 1.10.2020–30.9.2021
Total budget NIMH: 2 568 083 CZK

Stable and Mobile Devices to Support Circadian Synchronization, Treatment and Prevention of Mental Disorders Through Full-Spectrum Light Phototherapy (FW02020025)
Investigator: PhDr. Jana Kopřivová, Ph.D.
Principle investigator: Spectrasol, s.r.o.
Co-investigator-Partner: NIMH; Czech Technical University in Prague (University Centre for Energy Efficient Buildings)
Duration: 1.7.2020–30.9.2023
Total budget: 15 602 098 CZK
Total budget NIMH: 5 496 873 CZK

New Biochip and Microfluidic Diagnostics of Circulating Biomarkers and Pharmacogens in Psychiatric and Oncological Diseases (FW03010186)
Investigator: RNDr. Karel Valeš, Ph.D.
Principle investigator: ESSENCE LINE, s.r.o.
Co-investigator-Partner: NIMH; Masaryk University, Faculty of Medicine
Duration: 1.1.2021–31.12.2024
Total budget: 34 812 947 CZK
Total budget NIMH: 6 248 265 CZK