RP4 Epidemiological and Clinical Research in Addictions – Running Grants and Projects


The Czech Science Foundation

Socio-economic Determinants of Premature Mortality Related to Alcohol and Tobacco Use – Spatially Integrated Approach (18-17564S)
Investigator: Mgr. Ladislav Kážmér
Principle investigator: NIMH
Duration: 1.1.2018–31.12.2020
Total budget NIMH: 2 871 000 CZK
Abstract: Substance use is universally recognized as a leading cause of morbidity and premature death. From a global perspective, Czechia belongs to the countries with the highest per capita consumption of alcohol and tobacco. The level of substance use is considered to be influenced by both structural and environmental factors. Therefore, the focus of this project is a detailed evaluation of socio-spatial inequalities of substance-use-related premature mortality of the Czech population. Advanced statistical methods of spatial data analysis will be applied in the project. The main benefit will be the identification of compact micro-regions with a significantly increased mortality risk. The analysis will be conducted with a detailed spatial resolution at the municipal level. The project will also focus on 1.) mortality related to alcohol and tobacco; 2.) social composition of the population living in regions; 3.) gender specific differences; 4.) spatial-temporal changes after 2000. The project outcomes can serve for efficient planning of both socially and spatially targeted interventions.

Minority Stress in Non-heterosexuals in the Czech Republic (19-14801S)
Investigator: RNDr. Michal Pitoňák, Ph.D.
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 3 414 000 CZK
Abstract: Foreign studies have shown that non-heterosexuals, above all adolescents, have higher prevalence of mental disorders (depression, anxiety disorders), increased use of addictive substances (including tobacco and alcohol use) and higher suicidality compared to heterosexuals. These further correlate with a higher rate of risky sexual behavior, which increases the risk of transmission of sexually transmitted diseases (STDs), primarily HIV infection. These phenomena are repeatedly associated with so-called minority stress in foreign literature, which, in the population of non-heterosexuals, is beyond the stresses of other people. Verifying the theory of minority stress in the Czech Republic will contribute not only to increase of our understanding of the quality of mental health of non-heterosexuals and the efficiency and availability of preventive and therapeutic programs for this population that can contribute to mental well-being and reduction in psychiatric morbidity in this part of the population.


Government Council for Drug Policy Coordination

Development of an Effective Treatment Strategy for Methamphetamine Addiction (S-42-18) Investigator: PhDr. Ladislav Csémy
Principle investigator: NIMH
Duration: 1.1.2019–31.12.2021
Total budget NIMH: 583 000 CZK
Abstract: The project was initiated as a part of Czech-German scientific cooperation on the research of methamphetamine. The main objectives of this study are (1) to describe the socio-demographic and clinical factors associated with methamphetamine use, and (2) to evaluate existing and new treatments for methamphetamine dependence. Also, adapt and implement the US Methamphetamine Addiction Treatment Program: The Matrix Model for Meth Addiction Recovery.The project addresses methamphetamine users in outpatient and residential treatment, which will be monitored for 6 months. The profile of clients/patients, changes in the situation of clients / patients and their relationship to the characteristics of the client/patient at the beginning of treatment and the type of treatment used (therapeutic modalities based on the Matrix model vs. usual treatment in the facility) will be monitored.



European Commission

Supporting Wellbeing and Integration of Transgender Victims in Care environments with Holistic Approach (Justice 881635)
Investigator: PhDr. Pavla Doležalová, Ph.D.
Principle investigator: Perseo Spa Impresa Sociale (IT) Co-investigators/Partners: NIMH, Paradigma (IT), Fundacio Parc Tauli (S), Transparent z.s. (CR), Mirada Local SL (S), Azienda Unita Sanitaria Locale Di Reggio Emilia (IT)
Duration: 1.4.2020–31.3.202Total budget:516 542,5 Eur, EU subsidy 413 234 Eur
Total budget NIMH: 72 920,5 Eur, EU subsidy 58 336,4 Eur
Abstract: The general objective is to promote compassionate services to assist properly transgender and intersex survivors (TI) by enhancing competencies of psychiatrists, psychologists, psychotherapist and other social workers (direct target). TI people high exposition to discrimination and harassment exacerbate their risk for mental disorders, addictions and suicide (APA, 2015). Despite the need for healthcare assistance, the relationship with public services remains problematic, also due to the staffs’ implicit prejudices, and poor preparation (Carroll et al., 2012). The indirect target are TI victims of violence and their relatives. The project activities are: A model design including theoretical background, training system for professionals, supporting tools for TI; Training implementation including a training of trainers for trainers of the partnership and pilot training courses for the professionals involved; Networking and supporting tools implementation including MoU among public and private entities providing for TI supports, self-help groups promotion and information supports for both professionals and TI and their relatives; Results monitoring and dissemination. Expected outcomes are: Improvement of TI needs knowledge and awareness: 180 among professionals involved will be trained in the 3 partner Countries. They will be trained by 21 expert trainers coming from the SWITCH partnership; Start-up of a networking activity among public health care bodies and TI people private centres and associations including Recommendations to health care regional authorities in all Countries to support TI’s health ekvity; Improvement in wellbeing of TI victims through the start-up of 3 self-help groups in the partner Countries for about 90 TIs aiming identity integration and support; TI issues awareness increasing of the public: stakeholders of public and private of social health services as well as TI association will attend final workshops in the partner Countries.



RP1 Experimental Neurobiology RP2 Public Mental Health RP3 Applied Neuroscience and Neuroimaging RP4 Epidemiological and Clinical Research in Addictions RP5 Sleep Medicine and Chronobiology RP6 Brain Electrophysiology RP7 Clinical Research of Mental Disorders RP8 Translational Neuroscience International Cooperation Department AD Centrum Publications Ongoing Projects Pharmaceutical Industry-Sponsored Research Ethics Commission Postgraduate Students Conferences & Seminars Awards International Course 2015
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