doc. MUDr. Aleš Bartoš, Ph.D.
physician, researcher
working at:  Medical care: Dept. of Cognitive Disorders
RP7 Diagnostics and Treatment of Mental Disorders
in the institution:  2005 - present
telephone: (+420) 283 088 160
e-mail: ales.bartos@nudz.cz
curriculum vitae


Work experience

 

Dates

2015 →

Position held

member of committee for National plan for Alzheimer disease in the Czech Republic
in Ministry of Health

Dates

2005 →

Occupation or position held

senior researcher at National Institute of Mental Health, head of Department of cognitive disorders, AD Center

Main activities and responsibilities

conducting institutional, national and international research in neuroscience and neuropsychiatry, management of Department of cognitive disorders, AD Center

Name and address of employer

National Institute of Mental Health, Topolová 748, 250 67  Klecany, Czech Republic, Czech Republic

Type of business or sector

Research

Dates

1998 →

Occupation or position held

Associate Professor (2009-), Assistant Professor (1998-2009) in Neurology

Main activities and responsibilities

Education of medical students in basic and special neurology

Member of Board for State Examination of Neurobehavioral Sciences (2008-)

Deputy-Head of the Department of Neurology for research and science (2008-)

Tuition of pre- and postgraduate students in research (2004-)

Research in dementia and cognitive neurology, neuroimmunology

Name and address of employer

Charles University in Prague, Third Faculty of Medicine, Ruská 87, 100 00 Prague 10, Czech Republic

Type of business or sector

Education, research

Dates

1997 →

Occupation or position held

Board Certified Neurologist at the Department of Neurology

Head of Memory Clinic (2005-)

Main activities and responsibilities

Care for neurological patients, esp. those with cognitive disorders

Member of Multiple Sclerosis Center (1998-2006)

Name and address of employer

Univeristy Hospital Královské Vinohrady, Šrobárova 50, 100 34 Prague 10, Czech Republic

Type of business or sector

Medicine – neurology

Dates

1993 - 1997

Occupation or position held

Neurologist at the district Department of Neurology

Main activities and responsibilities

Care for neurological patients in general

Name and address of employer

Klaudian´s Hospital, V.Klementa street, Mladá Boleslav, Czech Republic

Type of business or sector

Medicine – neurology

 

 

Education and training

 

 

 

Dates

2004 - 2006

Title of qualification awarded

Ph.D.

Principal subjects / occupational skills covered

Research

Name and type of organisation providing education and training

Charles University in Prague, Third Faculty of Medicine, Ruská 87, 100 00 Prague 10, Czech Republic

 

 

Dates

1996-1999

Title of qualification awarded

Neurological Board Exam, 2nd degree with honour

Principal subjects / occupational skills covered

Advanced specialty in Neurology

Name and type of organisation providing education and training

Institute of Postgradual Education in Medicine, Ruská 85, 100 05 Prague 10, Czech Republic

 

 

Dates

1993-1996

Title of qualification awarded

Neurological Board Exam, 1st degree with honour

Principal subjects / occupational skills covered

Basic specialty in Neurology

Name and type of organisation providing education and training

Institute of Postgradual Education in Medicine, Ruská 85, 100 05 Prague 10, Czech Republic

 

 

Dates

1987-1993

Title of qualification awarded

Doctor of Medicine (M.D.)

Principal subjects / occupational skills covered

Undergradute university education in medicine

Name and type of organisation providing education and training

First Faculty of Medicine, Charles University, Kateřinská 32, 121 08 Prague 2, Czech Republic

Level in national or international classification

ISCED5

 

 

Personal skills and competences

 

 

 

Mother tongue(s)

Czech

 

 

Other language(s)

 

Self-assessmen

 

English

German

Understanding

Speaking

Writing

Listening

Reading

Spoken interaction

Spoken production

 

B1

Independent user

B1

Independent user

B1

Independent user

B1

Independent user

B1

Independent user

 

0

 

0

 

very basic

 

very basic

 

0

 

European level (*)

(*) Common European Framework of Reference (CEF) level

 

 

Social skills and competences

- I have established and initiated several research long-term collaborations

Organisational skills and competences

- I am/was the principle investigator of several research projects

- I have build up the team for cognitive research and care for the patients with cognitive disorders

- I am the Head of Memory Clinic and the Head of Department of cognitive disorders

- I have been coordinating the activities up to 20 colleagues

 

 

Computer skills and competences

I am fully  Microsoft Office and statistical software STATISTICA  literate.

Driving licence(s)

B

Additional information

 

Publications (the most relevant and recent ones only):

 

  1. Lenka Hromadkova, Michala Kolarova, Barbora Jankovicova, Ales Bartos, Jan Ricny, Zuzana Bilkova, Daniela Ripova.Identification and characterization of natural antibodies against tau protein in an intravenous immunoglobulin product. J Neuroimmunol 2015, in press
  2. Cantó E, Tintoré M, Villar LM, Costa C, Nurtdinov R, Álvarez-Cermeño JC, Arrambide G, Reverter F, Deisenhammer F, Hegen H, Khademi M, Olsson T, Tumani H, Rodríguez-Martín E, Piehl F, Bartos A et al. Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes. Brain. 2015;138(Pt 4):918-31. doi: 10.1093/brain/awv017, IF: 9.196/2014
  3. Stegurová L, Dráberová E, Bartos A, Dráber P, Rípová D, Dráber P. Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid. J Immunol Methods 2014;406: 137-142, doi: 10.1016/j.jim.2014.03.007
  4. Klener J, Hofbauerová K, Bartoš A, Ríčný J, Rípová D, Kopecký V. Instability of cerebrospinal fluid after delayed storage and repeated freezing: a holistic study by drop coating deposition Raman spectroscopy. Clin Chem Lab Med. 2014 1;52(5):657-64. doi: 10.1515/cclm-2013-0800
  5. Mrzílkova J, Koutela A, Kutová M, Patzelt M, Ibrahim I, Al-Kayssi D, Bartoš A, Řípová D, Čermáková P, Zach P. Hippocampal spatial position evaluation on MRI for research and clinical practice. PLoS ONE 2014; 9(12): e115174.
  6. Mrzílková J, Zach P, Bartoš A, Tintěra J, Řípová D. Volumetric analysis of the pons, cerebellum and hippocampi in patients with Alzheimer´s disease. Dementia and Geriatric Cognitive Disorders, 2012; 34(3-4): 224-234.
  7. Bartos A, Fialova L, Svarcova J, Ripova D. Patients with Alzheimer disease have elevated intrathecal synthesis of antibodies against tau protein and heavy neurofilament. J Neuroimmunol 2012; 252: 100-105, http://dx.doi.org/10.1016/j.jneuroim.2012.08.001.
  8. Kolarova M, Garcia-Sierra F, Bartoš A, Říčný J, Řípová D. Structure and pathology of tau protein in Alzheimer disease. International Journal of Alzheimer's Disease, 2012; 2012(ID 731526): 1-13.
  9. Hort J, Bartos A, Pirttilä T, Scheltens P. Use of cerebrospinal fluid biomarkers in diagnosis of dementia across Europe.Eur J Neurol 2010;17(1):90-6.

 

 

 

Scientific awards

  • 5 Czech Neurological Society Prizes for the best original paper awarded in 1999, 2003, 2004, 2005 and 2007
  • 2007 and 2008 tutor of 2 students achieving 1st and 2nd position at a student scientific conference
  • 2008 poster Bartos et al.: Visual rating and volumetry of hippocampus on magnetic resonance imaging in Alzheimer disease at 16th European Psychiatric Congress in Nice was awarded 1st prize for the best poster in Brain Imaging Section
  • 2007 tutor of a 3rd Medical Faculty student subsequently achieving 1st, 2nd and 3rd position at different student scientific conferences
  • 2006 Píchová R, Bartoš A et al: Relation between brain perfusion SPECT and Mini Mental State Examination in Alzheimer´s disease. The poster was evaluated as one of the best works at congress of the Association of Nuclear Medicine

 

 

Principal investigator or
co-investigator of the projects

Brief psychometric tools for early diagnostics of Alzheimer disease in senior population, 2012-2015

 

Use of neurocytoskeletal proteins and antibodies against them for diagnosis of Alzheimer disease, 2009-2011

 

Nano-PCR – ultrasensitive test for detection of specific proteins in body fluids, 2007-2011

Participation in clinical trials

2001-2004 : A prospective, multicentre, randomised, stratified, parallel group design, confirmatory study to investigate the effect of Octagam treatment (intravenous immunuglobulins) on the relapse rate during the postpartum period in patients suffering from relapsing/remitting multiple sclerosis („GAMPP Study“)

 

2002-2004: Double blind, placebo controlled, randomised, parallel group, multicenter, phase III study in patients with a first clinical demyelinating  roces suggestive of multiple sclerosis to evaluate the safety, tolerability, and efficiacy of 8 MIU (250 ug) interferon beta-1b (Betaferon/Betaseron) given subcutaneously every other day over a period of up to 24 months(„BENEFIT Study“)

 

2004-2005: Sativex Spasticity Study: A double blind, randomised, placebo controlled, parallel group study of Sativex, in subjects with symptoms of spasticity due to Multiple Sclerosis

 

2005-2007: “CogniMS” a “CogniCIS”: Observational study to assess cognition in patients with early multiple sclerosis

Awards and honors

2016 - 2016: The book by Doc. Ales Bartos, Ph.D. and Dr. Miloslava Rais, Ph.D .: The tests and questionnaires for examination of cognitive function, mood and self-sufficiency, Mlada fronta, 2015 was awarded the national psychiatric prize of professor Vladimir Vondracek in 2016 for best thesis on "Serious mental disorders - incidence, diagnosis and treatment "in the category of practical application.
2016 - 2016: The award for the best poster at the Days of Nuclear Medicine, 21.-23.9. 2016: Píchová R Fiser M Bartos A. Quantitative analysis of brain SPECT perfusion using software Neurogam in patients with Alzheimer's disease.
2016 - 2016: The award for the best poster at the 8th International Symposium on Clinical and Applied Anatomy in Budapest, 31.8-3 September 2016: Kuchtova B, Mrzilkova J, Z Wurst, A Bartos, Ibrahim I, Kieslich K, J Riedel, Janousek M, V Musil, Patzelt M, Zach P tractography of the fornix and subcallosus gyrus and paraterminalis in Patients with Alzheimer's disease.

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